The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Aug. 13, 2010
Applicants:
George Scott Wilson, Edinburgh, GB;
Maureen Joan Young, Edinburgh, GB;
Inventors:
George Scott Wilson, Edinburgh, GB;
Maureen Joan Young, Edinburgh, GB;
Assignee:
Johnson Matthey Public Limited Company, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 489/08 (2006.01); C07D 489/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for the reduction of a 6-keto group in a morphinan alkaloid to the corresponding 6-hydroxy group includes hydrogenating the 6-keto group using gaseous hydrogen in the presence of a heterogeneous catalyst and a solvent, to yield the 6-hydroxy morphinan alkaloid, wherein the reduction is carried out at a pH in the range of about 5 to about 7, and the 6-hydroxy morphinan alkaloid has an α:β ratio of >85:15.