The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Mar. 08, 2012
Applicant:
Francesco Fontana, Alte di Montecchio Maggiore, IT;
Inventor:
Francesco Fontana, Alte di Montecchio Maggiore, IT;
Assignee:
F.I.S. Fabbrica Italiana Sintetici S.p.A., Montecchio Maggiore (VI), IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 405/04 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 405/04 (2013.01); C07D 405/14 (2013.01);
Abstract
Methods for the synthesis of the pharmaceutically active ingredient Lapatinib and the salts thereof are provided. In particular, such methods utilize intermediates in which the hydroxyl function is protected by a tetrahydropyranyl group providing greater solubility of the intermediates in common organic solvents.