The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Sep. 17, 2009
Applicants:

Wangmao GE, Tampa, FL (US);

Pia M. Challita-eid, Encino, CA (US);

Arthur B. Raitano, Los Angeles, CA (US);

Aya Jakobovits, Beverly Hills, CA (US);

Inventors:

Wangmao Ge, Tampa, FL (US);

Pia M. Challita-Eid, Encino, CA (US);

Arthur B. Raitano, Los Angeles, CA (US);

Aya Jakobovits, Beverly Hills, CA (US);

Assignee:

Agensys, Inc., Santa Monica, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); A61K 39/00 (2006.01); A61K 51/10 (2006.01); C07K 16/30 (2006.01); C07K 14/705 (2006.01); G01N 33/574 (2006.01); C07K 14/47 (2006.01); G01N 33/566 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4748 (2013.01); A61K 39/0011 (2013.01); C07K 2316/96 (2013.01); A61K 51/1057 (2013.01); A61K 51/1072 (2013.01); C07K 16/3069 (2013.01); A61K 51/106 (2013.01); C07K 16/30 (2013.01); A61K 51/1051 (2013.01); C07K 14/705 (2013.01); G01N 33/57415 (2013.01); A61K 51/1054 (2013.01); A61K 2039/53 (2013.01); G01N 33/566 (2013.01);
Abstract

PSCA and its encoded protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.


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