The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Nov. 29, 2010
Applicants:

Jin-bin Wu, Taichung, TW;

Wen-chuan Lin, Taichung, TW;

Hui-ya Ho, Taichung, TW;

Sze-ying Chen, Taichung, TW;

Inventors:

Jin-Bin Wu, Taichung, TW;

Wen-Chuan Lin, Taichung, TW;

Hui-Ya Ho, Taichung, TW;

Sze-Ying Chen, Taichung, TW;

Assignee:

China Medical University, Taichung, TW;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/191 (2006.01); A61P 17/00 (2006.01); A61Q 19/08 (2006.01); A61K 8/365 (2006.01); C07C 61/29 (2006.01); A61K 31/19 (2006.01); A61K 8/63 (2006.01);
U.S. Cl.
CPC ...
A61K 8/63 (2013.01); A61Q 19/08 (2013.01); A61K 31/19 (2013.01); A61K 2800/782 (2013.01);
Abstract

A method for inhibiting the activity of matrix metalloproteinase (MMP), inhibiting the expression of matrix metalloproteinase, inhibiting the phosphorylation of mitogen-activated protein kinase (MAPK), and/or promoting the expression of collagen in a mammal is provided. The method comprises administrating to the mammal an effective amount of an active component selected from a group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound, and combinations thereof:


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