The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Apr. 23, 2010
Applicants:

Jae-kwan Hwang, Gyeonggi-do, KR;

Do-un Kim, Gyeonggi-do, KR;

Jae-youn Chung, Seoul, KR;

Hee-chul Chung, Gyeonggi-do, KR;

Kyu-lee Han, Seoul, KR;

Inventors:

Jae-Kwan Hwang, Gyeonggi-do, KR;

Do-Un Kim, Gyeonggi-do, KR;

Jae-Youn Chung, Seoul, KR;

Hee-Chul Chung, Gyeonggi-do, KR;

Kyu-Lee Han, Seoul, KR;

Assignees:

Newtree Industry Co., Ltd., Sungnam, KR;

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/185 (2006.01); A61K 31/36 (2006.01); A61P 17/00 (2006.01); A61P 29/00 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 31/36 (2013.01); A61K 9/0095 (2013.01); A61K 9/2054 (2013.01); A61K 36/185 (2013.01); Y10S 514/859 (2013.01); Y10S 514/886 (2013.01);
Abstract

The present invention relates to the use of lignan compounds for treating or preventing an inflammatory disease. More particularly, it relates to a method for preventing or treating an inflammatory disease, comprising administering to a subject in need thereof an effective amount of macelignan represented by Chemical Formula I or a pharmaceutically acceptable salt thereof. The lignan compound has the effect of inhibiting inflammatory reactions by inhibiting the production or expression of inflammation mediators NO, iNOS, PGE, COX-2 and TNF-α and by treating or preventing inflammatory disease in vivo. Accordingly, the lignan compound or aextract will be highly useful for the treatment or prevention of an inflammatory disease.


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