The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Oct. 04, 2010
Applicants:
Matthew Frank Brown, Stonington, CT (US);
Anthony Marfat, Mystic, CT (US);
Michael Joseph Melnick, Portage, MI (US);
Usa Reilly, West Haven, CT (US);
Inventors:
Matthew Frank Brown, Stonington, CT (US);
Anthony Marfat, Mystic, CT (US);
Michael Joseph Melnick, Portage, MI (US);
Usa Reilly, West Haven, CT (US);
Assignee:
Pfizer Inc., New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/382 (2006.01); A61K 31/47 (2006.01); A61K 31/661 (2006.01); C07D 215/06 (2006.01); C07C 317/44 (2006.01); C07D 231/56 (2006.01); C07F 9/12 (2006.01); C07C 323/65 (2006.01); C07C 317/46 (2006.01); C07D 213/56 (2006.01); C07C 317/48 (2006.01); C07D 263/08 (2006.01); C07D 295/03 (2006.01); C07D 263/20 (2006.01); C07D 335/02 (2006.01); C07D 213/30 (2006.01);
U.S. Cl.
CPC ...
C07C 317/44 (2013.01); C07D 231/56 (2013.01); C07F 9/12 (2013.01); C07C 323/65 (2013.01); C07C 317/46 (2013.01); C07C 2101/08 (2013.01); C07D 213/56 (2013.01); C07C 317/48 (2013.01); C07D 263/08 (2013.01); C07D 295/03 (2013.01); C07D 263/20 (2013.01); C07D 215/06 (2013.01); C07D 335/02 (2013.01); C07D 213/30 (2013.01); C07C 2101/18 (2013.01); C07C 2101/02 (2013.01);
Abstract
The present invention is directed to a new class of hydroxamic acid derivatives of Formula I, wherein the variables G, T, D, L, A, X, Rand Rare as described hereinabove, and their use as LpxC inhibitors, and more specifically their use to treat bacterial infections.