The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Dec. 14, 2010
Applicants:
Markus Kalesse, Burgdorf, DE;
Ulrike Eggert, Hannover, DE;
Inventors:
Markus Kalesse, Burgdorf, DE;
Ulrike Eggert, Hannover, DE;
Assignees:
Helmholtz-Zentrum für Infektionsforschungs GmbH, Braunschweig, DE;
Medizinische Hochschule Hannover, Hannover, DE;
Gottfried Wilhelm Leibniz Universität, Hannover, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/429 (2006.01); C07D 513/08 (2006.01); C07D 209/20 (2006.01); C07B 53/00 (2006.01);
U.S. Cl.
CPC ...
C07B 53/00 (2013.01); C07D 209/20 (2013.01); C07D 513/08 (2013.01);
Abstract
The present invention relates to an improved method for the synthesis of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular argyrin and derivatives thereof.