The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Sep. 07, 2007
Keith Clinch, Lower Hutt, NZ;
Gary Brian Evans, Lower Hutt, NZ;
Richard Hubert Furneaux, Wellington, NZ;
Shivali Ashwin Gulab, Wellington, NZ;
Peter Michael Kelly, Wellington, NZ;
Vern L. Schramm, New Rochelle, NY (US);
Peter Charles Tyler, Wellington, NZ;
Anthony David Woolhouse, Wellington, NZ;
Keith Clinch, Lower Hutt, NZ;
Gary Brian Evans, Lower Hutt, NZ;
Richard Hubert Furneaux, Wellington, NZ;
Shivali Ashwin Gulab, Wellington, NZ;
Peter Michael Kelly, Wellington, NZ;
Vern L. Schramm, New Rochelle, NY (US);
Peter Charles Tyler, Wellington, NZ;
Anthony David Woolhouse, Wellington, NZ;
Industrial Research Limited, Lower Hutt, NZ;
Albert Einstein College of Medicine of Yeshiva University, Bronx, NY (US);
Abstract
The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.