The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Feb. 17, 2011
Robert R. Wilkening, Maplewood, NJ (US);
James M. Apgar, Highland Park, NJ (US);
Tesfaye Biftu, Freehold, NJ (US);
Danqing Feng, Green Brook, NJ (US);
Xiaoxia Qian, New York, NY (US);
Lan Wei, Edison, NJ (US);
Robert R. Wilkening, Maplewood, NJ (US);
James M. Apgar, Highland Park, NJ (US);
Tesfaye Biftu, Freehold, NJ (US);
Danqing Feng, Green Brook, NJ (US);
Xiaoxia Qian, New York, NY (US);
Lan Wei, Edison, NJ (US);
Merck Sharp & Dohme Corp, Rahway, NJ (US);
Abstract
The present invention is directed to novel substituted aminotetrahydrothiopyrans and derivatives thereof of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.