The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Apr. 15, 2011
Xiaohong Song, Grayslake, IL (US);
Hong Ding, Gurnee, IL (US);
Steven W. Elmore, Northbrook, IL (US);
Milan Bruncko, Green Oaks, IL (US);
David J. Madar, Gilbert, AZ (US);
Andrew J. Souers, Evanston, IL (US);
Cheol-min Park, Singapore, SG;
Zhi-fu Tao, Gurnee, IL (US);
Xilu Wang, Grayslake, IL (US);
Aaron R. Kunzer, Shaumburg, IL (US);
Xiaohong Song, Grayslake, IL (US);
Hong Ding, Gurnee, IL (US);
Steven W. Elmore, Northbrook, IL (US);
Milan Bruncko, Green Oaks, IL (US);
David J. Madar, Gilbert, AZ (US);
Andrew J. Souers, Evanston, IL (US);
Cheol-Min Park, Singapore, SG;
Zhi-Fu Tao, Gurnee, IL (US);
Xilu Wang, Grayslake, IL (US);
Aaron R. Kunzer, Shaumburg, IL (US);
AbbVie Inc., North Chicago, IL (US);
Abstract
Compounds of Formula I wherein A, B, C, D, E, Fand Lare as defined herein, which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds, and methods of treating diseases involving overexpressed or unregulated Mdl-1 protein, such as leukemia and lymphoma, are disclosed.