The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Nov. 11, 2013
Les Laboratoires Servier, Suresnes Cedex, FR;
Armgo Pharma, Inc., Tarrytown, NY (US);
Jiaming Yan, New York, NY (US);
Sandro Belvedere, New York, NY (US);
Yael Webb, Yorktown Heights, NY (US);
Marc Bertrand, Saint Jean le Blanc, FR;
Nicole Villeneuve, Rueil Malmaison, FR;
Les Laboratoires Servier, Suresnes Cedex, FR;
ARMGO Pharma, Inc., Tarrytown, NY (US);
Abstract
The present invention relates to 1,4-benzothiazepine derivatives and their use to treat conditions, disorders and diseases associated with ryanodine receptors (RyRs) that regulate calcium channel functioning in cells. The invention also discloses pharmaceutical compositions comprising the compounds and uses thereof to treat diseases and conditions associated with RyRs, in particular cardiac, musculoskeletal and central nervous system (CNS) disorders.