The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Feb. 18, 2011
Applicants:

Masaki Mori, Osaka, JP;

Hideshi Ishii, Osaka, JP;

Norikatsu Miyoshi, Osaka, JP;

Yuichiro Doki, Osaka, JP;

Masahiro Tanemura, Osaka, JP;

Kenichi Nagai, Osaka, JP;

Hiromitsu Hoshino, Osaka, JP;

Yoshiaki Omura, Osaka, JP;

Naotsugu Haraguchi, Osaka, JP;

Susumu Miyazaki, Osaka, JP;

Inventors:

Masaki Mori, Osaka, JP;

Hideshi Ishii, Osaka, JP;

Norikatsu Miyoshi, Osaka, JP;

Yuichiro Doki, Osaka, JP;

Masahiro Tanemura, Osaka, JP;

Kenichi Nagai, Osaka, JP;

Hiromitsu Hoshino, Osaka, JP;

Yoshiaki Omura, Osaka, JP;

Naotsugu Haraguchi, Osaka, JP;

Susumu Miyazaki, Osaka, JP;

Assignee:

Osaka University, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/07 (2010.01); C12N 15/00 (2006.01); G01N 33/50 (2006.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C12N 2501/65 (2013.01); C12N 2506/1384 (2013.01); G01N 33/5008 (2013.01); C12N 2506/1307 (2013.01);
Abstract

A major object of the present invention is to provide a method for producing induced pluripotent stem cells with low tumorigenesis potential and high induction efficiency. The invention provides a method for producing induced pluripotent stem cells comprising the step of introducing one or more nucleic acids that facilitate expression of at least one gene selected from the group consisting of NANOG, SOX2, OCT3/4, KLF4, LIN28, and c-MYC into somatic cells.


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