The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Feb. 16, 2010
Applicants:

Diana Hall, Lausanne, CH;

Maria Jimenez, Chavannes-pres-renens, CH;

Carine Poussin, Evian-les-Bains, FR;

Bernard Thorens, Epalinges, CH;

Inventors:

Diana Hall, Lausanne, CH;

Maria Jimenez, Chavannes-pres-renens, CH;

Carine Poussin, Evian-les-Bains, FR;

Bernard Thorens, Epalinges, CH;

Assignee:

Sanofi, Paris, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A01N 63/00 (2006.01); C12N 5/02 (2006.01); C12P 21/04 (2006.01); C07K 14/46 (2006.01); G01N 33/68 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6872 (2013.01); C07K 14/46 (2013.01); G01N 2800/044 (2013.01); G01N 33/53 (2013.01); C12N 2800/107 (2013.01); A61K 48/005 (2013.01);
Abstract

The present invention concerns Vgll3 a new target involved in adipogenesis modulation. Further, the present invention relates to methods to increase Vgll3 activity in adipocytes and preadipocytes. In addition, pharmaceutical composition comprising Vgll3 activity enhancing molecules in order to enhance the Vgll3 activity in a target tissue are also provided. These methods, compositions and molecules can be useful to modulate adipogenesis and thus treat obesity and related disorders.


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