The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Jun. 21, 2012
Gabor Forgacs, Columbia, MO (US);
Karoly Jakab, Columbia, MO (US);
Adrian Neagu, Columbia, MO (US);
Vladimir Mironov, Mount Pleasant, SC (US);
Gabor Forgacs, Columbia, MO (US);
Karoly Jakab, Columbia, MO (US);
Adrian Neagu, Columbia, MO (US);
Vladimir Mironov, Mount Pleasant, SC (US);
The Curators of the University of Missouri, Columbia, MO (US);
Medical University of South Carolina, Charleston, SC (US);
MUSC Foundation for Research Development, Charleston, SC (US);
Abstract
A method of making engineered tissue from a plurality of cell aggregates is disclosed. A cell suspension is centrifuged. The resulting pellet is extruded through an orifice, and the extruded pellet is cut into pieces to produce cell aggregates. A plurality of the cell aggregates are printed in a pattern, and allowed to fuse to form a desired three-dimensional engineered tissue structure. Modeling methods predict the structural evolution of fusing cell aggregates for combinations of cell type to enable selection of organ printing process parameters for use in producing an engineered tissue having a desired three-dimensional structure.