The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Jul. 02, 2008
Applicants:
Alexander Emelyanov, Singapore, SG;
Sergey Parinov, Singapore, SG;
Nam-hai Chua, New York, NY (US);
Inventors:
Assignee:
Temasek Life Sciences Laboratory Limited, Singapore, SG;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/85 (2006.01); A01K 67/027 (2006.01); A01K 67/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C07K 2319/71 (2013.01); C12N 2800/40 (2013.01); C07K 2319/715 (2013.01); A01K 2227/40 (2013.01); A01K 2217/15 (2013.01); A01K 2267/03 (2013.01); C12N 15/8509 (2013.01); A01K 67/0275 (2013.01); C12N 2830/002 (2013.01); A01K 2217/052 (2013.01); A01K 2217/203 (2013.01); C07K 2319/80 (2013.01); A01K 2267/0393 (2013.01);
Abstract
The present invention relates generally to chemical-inducible system and to methods of use in transgenic animals. More specifically, the present invention relates to a chimeric transcription factor that binds to a ligand and functions in ligand-dependent manner to induce expression of genes of interest under the control of a synthetic operator-promoter sequence. The expression of genes of interest can be tightly controlled by adding or removing the ligand.