The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Dec. 03, 2010
Applicants:

Steven M. Boronyak, Kingwood, TX (US);

George C. Engelmayr, Jr., Cambridge, MA (US);

Sharan Ramaswamy, Miami, FL (US);

Michael S. Sacks, Pittsburgh, PA (US);

David E. Schmidt, Pittsburgh, PA (US);

Mohammed S. El-kurdi, Pittsburgh, PA (US);

Inventors:

Steven M. Boronyak, Kingwood, TX (US);

George C. Engelmayr, Jr., Cambridge, MA (US);

Sharan Ramaswamy, Miami, FL (US);

Michael S. Sacks, Pittsburgh, PA (US);

David E. Schmidt, Pittsburgh, PA (US);

Mohammed S. El-Kurdi, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); C12M 1/24 (2006.01); C12M 1/42 (2006.01);
U.S. Cl.
CPC ...
C12M 21/08 (2013.01); C12M 23/08 (2013.01); C12M 35/04 (2013.01);
Abstract

Described herein is a bioreactor system and modules capable of developing physiologically relevant fluid-induced shear stresses and regionally specific flow patterns to scaffold specimens and which can couple these stresses to cyclic flexure and/or stretch states. Methods of use of the bioreactor system and module also are provided.


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