The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Aug. 03, 2011
Applicants:

Jean-michel Itier, Savigny sur Orge, FR;

Marie-christine Multon, Versailles, FR;

Gwénaëlle Ret, Naisons-Alfort, FR;

Jean-marie Stutzmann, Villecresnes, FR;

Florence Wahl, Boulogne, FR;

Inventors:

Jean-Michel Itier, Savigny sur Orge, FR;

Marie-Christine Multon, Versailles, FR;

Gwénaëlle Ret, Naisons-Alfort, FR;

Jean-Marie Stutzmann, Villecresnes, FR;

Florence Wahl, Boulogne, FR;

Assignee:

Aventis Pharma S.A., Antony, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/567 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); G01N 2333/4703 (2013.01); G01N 33/6896 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01); G01N 33/6872 (2013.01);
Abstract

The invention concerns the use of whole or part of the GRF1 protein, or of cells expressing whole or part of the GRF1 protein, in methods for detecting compounds for preventing and/or treating pathologies or disorders of the central nervous system involving neuronal death, such as apoptosis, or related to leptin metabolism. The pathologies of the central nervous system are in particular cerebral ischemia, Parkinson's disease or Alzheimer's disease.


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