The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
May. 22, 2012
Applicants:
Qian Zhang, Danville, CA (US);
Sanjeev Gangwar, Foster City, CA (US);
Chin Pan, Los Altos, CA (US);
Daniel W. Derwin, San Francisco, CA (US);
Inventors:
Qian Zhang, Danville, CA (US);
Sanjeev Gangwar, Foster City, CA (US);
Chin Pan, Los Altos, CA (US);
Daniel W. Derwin, San Francisco, CA (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 7/06 (2006.01); C07K 5/08 (2006.01); C07K 16/18 (2006.01); C07F 9/572 (2006.01); A61P 35/00 (2006.01); C07K 5/10 (2006.01); A61K 47/48 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 209/60 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48615 (2013.01); A61K 47/48569 (2013.01); A61K 47/48592 (2013.01); A61K 47/48384 (2013.01); C07D 403/06 (2013.01); A61K 47/486 (2013.01); C07D 403/14 (2013.01); A61K 47/48638 (2013.01); C07D 209/60 (2013.01);
Abstract
An immunoconjugate in which a phosphate-prodrugged DNA minor groove binding agent of formula (I), where X is a nucleophilically displaceable leaving group, is conjugated to an antibody or an antigen binding fragment of an antibody, and compounds that can be used for making such immunoconjugates, and uses of such immunoconjugates.