The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Oct. 15, 2012
Applicant:

The United States of America, As Represented BY the Secretary of Agriculture, Washington, DC (US);

Inventors:

Mark C. Jenkins, Davidsonville, MD (US);

Ronald Fayer, Ellicot City, MD (US);

Monica Santin, Odenton, MD (US);

Dumitru Macarisin, Hagerstown, MD (US);

Celia O'Brien, Ellicott City, MD (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

Immunolocalization of β- and δ-giardin introphozoites revealed that both giardins are strictly associated with the ventral disc. Optical sectioning of immunolabeled ventral disc, together with quantitative co-localization of δ- and β-giardin immunoreactivity, demonstrated that δ-giardin is primarily localized to the ventral side, and β-giardin is localized to the dorsal side of the ventral disc. Antibodies to δ-giardin and β-giardin can both be used as diagnostic agents; anti-δ-giardin antibody can be used as a therapeutic reagent to inhibit binding of trophozoites to host cells.


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