The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Oct. 08, 2010
Tin-yun Ho, Taichung, TW;
Chien-yun Hsiang, Taichung, TW;
Shih-lu Wu, Taichung, TW;
Ji-an Liang, Taichung, TW;
Chia-cheng LI, Taichung, TW;
Hsin-yi Lo, Taichung, TW;
Tin-Yun Ho, Taichung, TW;
Chien-Yun Hsiang, Taichung, TW;
Shih-Lu Wu, Taichung, TW;
Ji-An Liang, Taichung, TW;
Chia-Cheng Li, Taichung, TW;
Hsin-Yi Lo, Taichung, TW;
China Medical University, Taichung, TW;
Abstract
A modified sodium iodide symporter (NIS) protein is provided. The modified NIS protein comprises an amino acid sequence of SEQ ID NO.1 with the proviso that at least one amino acid residue within SEQ ID NO. 1 is changed. The modified NIS protein has an enhanced transport function, and the expression of the modified NIS protein in the cells results in higher intracellular levels of a substrate of a NIS protein than does the expression of the same amount of a wild-type NIS protein.