The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Oct. 27, 2010
Applicants:

José Ignacio Andrés-gil, Madrid, ES;

Meri DE Angelis, Toledo, ES;

Guy Maurits R. Bormans, Rotselaar, BE;

Sofie Jeanne Leopoldine Celen, Tessenderlo, BE;

Inventors:

José Ignacio Andrés-Gil, Madrid, ES;

Meri De Angelis, Toledo, ES;

Guy Maurits R. Bormans, Rotselaar, BE;

Sofie Jeanne Leopoldine Celen, Tessenderlo, BE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 51/0455 (2013.01);
Abstract

The present invention relates to novel, selective, radiolabelled PDE10 ligands which are useful for imaging and quantifying the PDE10A enzyme in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo.


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