The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2014
Filed:
Apr. 27, 2007
Agnès Vignery, Branford, CT (US);
Nozer M. Mehta, Randolph, NJ (US);
James P. Gilligan, Union, NJ (US);
Kieran P. Murphy, Baltimore, MD (US);
Agnès Vignery, Branford, CT (US);
Nozer M. Mehta, Randolph, NJ (US);
James P. Gilligan, Union, NJ (US);
Kieran P. Murphy, Baltimore, MD (US);
Kieran Murphy, LLC, Towson, MD (US);
Yale University, New Haven, CT (US);
Abstract
A method for augmenting bone in a subject in need thereof including installing within an interior portion of a bone located in the subject a sufficient amount of a biocompatible material to form a scaffold within the bone interior, wherein the scaffold serves as a support for the formation of new bone within the bone interior portion, and administering to the subject a sufficient amount of at least one bone augmentation agent to elevate blood concentration of at least one anabolic agent in the subject. The method may further include administering at least one anti-resorptive agent to the subject in an amount sufficient to substantially prevent resorption of new bone growth. In another embodiment, the method may further include a step of mechanically inducing an increase in osteoblast activity in the subject, wherein the elevation in blood concentration of the anabolic agent and the increase in osteoblast activity at least partially overlap in time.