The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2014

Filed:

Jun. 17, 2009
Applicants:

Yuejun Xiang, Bayside, NY (US);

Praveen Pande, Holbrook, NY (US);

Rajesh Khazanchi, Islandia, NY (US);

Elazar Rabbani, New York, NY (US);

Dakai Liu, South Setauket, NY (US);

Wei Cheng, Jericho, NY (US);

Inventors:

Yuejun Xiang, Bayside, NY (US);

Praveen Pande, Holbrook, NY (US);

Rajesh Khazanchi, Islandia, NY (US);

Elazar Rabbani, New York, NY (US);

Dakai Liu, South Setauket, NY (US);

Wei Cheng, Jericho, NY (US);

Assignee:

Enzo Life Sciences, Inc., Farmingdale, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/14 (2006.01); C07D 235/20 (2006.01); C07D 277/68 (2006.01); C07D 263/54 (2006.01); C07D 417/14 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 417/06 (2006.01); C09B 23/01 (2006.01); C09B 23/04 (2006.01); C09B 23/06 (2006.01); C09B 23/08 (2006.01); C09B 23/10 (2006.01); C09B 23/14 (2006.01); C07H 19/10 (2006.01); C07H 21/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 209/14 (2013.01); C07D 235/20 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 417/06 (2013.01); C09B 23/0091 (2013.01); C09B 23/04 (2013.01); C09B 23/06 (2013.01); C09B 23/083 (2013.01); C09B 23/105 (2013.01); C09B 23/145 (2013.01); C09B 23/146 (2013.01); C07H 19/10 (2013.01); C07H 21/00 (2013.01); C07K 14/00 (2013.01); C07K 16/00 (2013.01);
Abstract

The present invention provides dyes, reactive dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins and nucleic acids. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes are also provided that comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been modified by the addition of charged and polar groups to provide beneficial properties.


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