The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2014

Filed:

Feb. 11, 2011
Applicants:

David A. Schwartz, Encinitas, CA (US);

Leopoldo G. Mendoza, Scottsdale, AZ (US);

Inventors:

David A. Schwartz, Encinitas, CA (US);

Leopoldo G. Mendoza, Scottsdale, AZ (US);

Assignee:

Solulink, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/00 (2006.01); C07K 1/22 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/484 (2013.01); C07K 2319/20 (2013.01); C07K 2319/43 (2013.01); C07K 2319/41 (2013.01); C07K 1/22 (2013.01); A61K 47/48507 (2013.01); C07K 2319/21 (2013.01);
Abstract

Methods, systems and/or kits for the preparation, purification and isolation of oligonucleotide conjugates, comprising conjugation of modified antibodies or proteins with at least one modified oligonucleotide at greater than 80% efficiency to form oligonucleotide conjugates and isolating the oligonucleotide conjugates from the conjugation solution by binding the conjugates to an immobilized binder, wherein the binder may be a metal ion or an antibody.


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