The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2014

Filed:

Aug. 24, 2010
Applicants:

Yves Briers, Rohr AG, CH;

Rob Lavigne, Merksem, BE;

Maarten Walmagh, Herk-de-Stad, BE;

Stefan Miller, Regensburg, DE;

Inventors:

Yves Briers, Rohr AG, CH;

Rob Lavigne, Merksem, BE;

Maarten Walmagh, Herk-de-Stad, BE;

Stefan Miller, Regensburg, DE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/43 (2006.01); C07K 14/00 (2006.01); C12N 9/26 (2006.01); A61K 38/00 (2006.01); A61K 38/04 (2006.01); C12N 9/36 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2462 (2013.01); A61K 38/00 (2013.01); C12Y 302/01017 (2013.01);
Abstract

The present invention relates to a polypeptide with an amino acid sequence according to SEQ ID NO: 1 and fragments or derivatives thereof. The present invention further relates to fusion proteins comprising said polypeptide and an additional peptide stretch fused to said polypeptide at the N- or C-terminus. Moreover, the present invention relates to nucleic acid molecules encoding said polypeptide or fusion protein, vectors comprising said nucleic acid molecules and host cells comprising either said nucleic acid molecules or said vectors. In addition, the present invention relates to said polypeptide or fusion protein for use as a medicament, in particular for the treatment or prevention of Gram-negative bacterial infections, as diagnostic means, as cosmetic substance or as sanitizing agent. The present invention also relates to the use of said polypeptide or fusion protein for the treatment or prevention of Gram-negative bacterial contamination of foodstuff, of food processing equipment, of food processing plants, of surfaces coming into contact with foodstuff, of medical devices, of surfaces in hospitals and surgeries. Furthermore, the present invention relates to a pharmaceutical composition comprising said polypeptide or fusion protein.


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