The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2014
Filed:
Feb. 19, 2013
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
William L. Murphy, Waunakee, WI (US);
Jae Sung Lee, Middleton, WI (US);
Mark D. Markel, Middleton, WI (US);
Ben K. Graf, Madison, WI (US);
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 2/00 (2006.01); C07K 14/00 (2006.01); C07K 9/00 (2006.01); C07K 14/51 (2006.01); B05D 1/18 (2006.01); C07K 14/52 (2006.01); B05D 1/28 (2006.01); C07K 14/50 (2006.01);
U.S. Cl.
CPC ...
B05D 1/18 (2013.01); C07K 14/51 (2013.01); C07K 14/52 (2013.01); B05D 1/28 (2013.01); C07K 14/50 (2013.01);
Abstract
A modular peptide design strategy wherein the modular peptide has two functional units separated by a spacer portion is disclosed. More particularly, the design strategy combines a hydroxyapatite-binding portion and a biomolecule-derived portion. The modular peptides have improved non-covalent binding to the surface of the HA-based materials, and are capable of initiating osteogenesis, angiogenesis, and/or osteogenic differentiation.