The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2014

Filed:

Jun. 12, 2013
Applicant:

Roche Palo Alto Llc, So. San Francisco, CA (US);

Inventors:

Bernd Buettelmann, Schopfheim, DE;

Roland Jakob-Roetne, Inzlingen, DE;

Henner Knust, Rheinfelden, DE;

Matthew C. Lucas, Lexington, MA (US);

Andrew Thomas, Binningen, CH;

Assignee:

Roche Palo Alto LLC, So. San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4427 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is concerned with isoxazole-pyridine derivatives of formula I wherein X, Rto Rare as described herein. The compounds are active on the GABA A α5 receptor binding site and useful for the treatment of cognitive disorders, such as Alzheimer's disease.


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