The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2014

Filed:

Nov. 17, 2006
Applicants:

Ernst Wulfert, Brussels, BE;

James Robert Murray, Bristol, GB;

David Wynick, Bristol, GB;

Inventors:

Ernst Wulfert, Brussels, BE;

James Robert Murray, Bristol, GB;

David Wynick, Bristol, GB;

Assignee:

Hunter-Fleming Limited, Bristol, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A61K 31/33 (2006.01); A61K 31/56 (2006.01); A61K 31/568 (2006.01); A61K 31/573 (2006.01);
U.S. Cl.
CPC ...
A61K 31/568 (2013.01); A61K 31/573 (2013.01);
Abstract

A steroid derivative compound of formula (I) in which: one of Rand Ris hydroxy and the other is hydrogen; or Rand Rtogether represent oxo; Ris hydrogen or hydroxy; and the dotted lines represent single or double carbon-carbon bonds; and pharmaceutically acceptable salts and esters thereof are useful for the prevention or treatment of pain, for improving nerve regeneration after nerve injury or damage or disease, for the prevention or treatment of brain injury, damage or disease and for neuroprotection. Particularly useful compounds are 11-hydroxy-Δ4-androstene-3,17-dione and 11-oxo-Δ4-androstene-3,17-dione or their derivatives.


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