The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2014
Filed:
Nov. 07, 2012
Applicant:
Taipei Veterans General Hospital, Taipei, TW;
Inventors:
Assignee:
Taipei Veterans General Hospital, Taipei, TW;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 31/7088 (2006.01); C07H 21/02 (2006.01); A61K 31/7105 (2006.01); C12N 5/09 (2010.01); A61K 47/34 (2006.01); A61K 31/495 (2006.01); A61K 9/50 (2006.01); C12N 5/095 (2010.01);
U.S. Cl.
CPC ...
A61K 31/7088 (2013.01); C07H 21/02 (2013.01); A61K 31/7105 (2013.01); C12N 2501/65 (2013.01); C12N 5/0693 (2013.01); A61K 47/34 (2013.01); A61K 31/495 (2013.01); A61K 9/5031 (2013.01); C12N 5/0695 (2013.01);
Abstract
The present invention provides a method for inhibiting cancer stem cell like properties and chemoradioresistant properties of cancer or tumor cells comprising delivering miR145 to the cancer or tumor cells, particularly brain tumor and head and neck cancer cells. The invention further provides a pharmaceutical composition comprising miR145 and a method for treating brain tumor and/or head and neck cancer comprising administration of miR145 to a subject in need thereof.