The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2014
Filed:
Jun. 19, 2012
Victor J. Torres, New York, NY (US);
Derya Unutmaz, New York, NY (US);
Francis Alonzo, Iii, New York, NY (US);
Victor J. Torres, New York, NY (US);
Derya Unutmaz, New York, NY (US);
Francis Alonzo, III, New York, NY (US);
New York University, New York, NY (US);
Abstract
The present invention relates to methods for preventing or treating Human Immunodeficiency Virus (HIV) infection, inflammatory conditions, and graft-versus-host-disease (GVHD) in a subject. Therapeutic compositions of the present invention comprise Leukocidin E (LukE) and/or D proteins or polypeptides. The invention further relates to methods of treatinginfection by administering a composition comprising a CCR5 antagonist or any molecule that blocks LukE/D interaction with CCR5cells in an amount effective to treat theinfection in the subject.