The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2014
Filed:
Nov. 11, 2008
Applicants:
Sanjay Mistry, Downingtown, PA (US);
Darin J. Messina, Downingtown, PA (US);
Inventors:
Sanjay Mistry, Downingtown, PA (US);
Darin J. Messina, Downingtown, PA (US);
Assignee:
Ethicon, Inc., Somerville, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/07 (2010.01); A61K 38/18 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1875 (2013.01); A61K 38/1825 (2013.01); A61K 38/1709 (2013.01);
Abstract
The present invention is directed to methods of treating neurological deficits resulting from injury or disease to the striatum or substanta nigra pars compacta of a human by administering human recombinant GDF5 to the striatum or substanta nigra pars compacta of a human in amounts effective to induce cell populations having the capacity to differentiate towards a dopaminergic phenotype to in fact differentiate towards a dopaminergic phenotype, and to neurotrophic compositions and matrices suitable for use in such treatments.