The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2014

Filed:

May. 23, 2006
Applicants:

Ernest M. Wright, Los Angeles, CA (US);

Jorge R. Barrio, Agoura Hills, CA (US);

Bruce A. Hirayama, Los Angeles, CA (US);

Vladimir Kepe, Los Angeles, CA (US);

Inventors:

Ernest M. Wright, Los Angeles, CA (US);

Jorge R. Barrio, Agoura Hills, CA (US);

Bruce A. Hirayama, Los Angeles, CA (US);

Vladimir Kepe, Los Angeles, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); G01N 33/60 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/60 (2013.01); G01N 33/6872 (2013.01); G01N 2400/00 (2013.01);
Abstract

Radiolabeled tracers for sodium/glucose cotransporters (SGLTs), their synthesis, and their use are provided. The tracers are methyl or ethyl pyranosides having an equatorial hydroxyl group at carbon-2 and a C 1 preferred conformation, radiolabeled withF,I, orI, or free hexoses radiolabeled withF,I, or. Also provided are in vivo and in vitro techniques for using these and other tracers as analytical and diagnostic tools to study glucose transport, in health and disease, and to evaluate therapeutic interventions.


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