The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2014
Filed:
Apr. 26, 2012
Applicants:
Elliot Botvinick, Irvine, CA (US);
Samir Shreim, Irvine, CA (US);
Maxwell Kotlarchyk, Costa Mesa, CA (US);
Inventors:
Elliot Botvinick, Irvine, CA (US);
Samir Shreim, Irvine, CA (US);
Maxwell Kotlarchyk, Costa Mesa, CA (US);
Assignee:
The Regents of The University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/24 (2006.01); C12M 1/42 (2006.01); A61L 27/36 (2006.01); G01N 11/14 (2006.01);
U.S. Cl.
CPC ...
G01N 3/24 (2013.01); C12M 35/04 (2013.01); A61L 27/3691 (2013.01); G01N 11/14 (2013.01); G01N 2203/0089 (2013.01);
Abstract
An apparatus and method for providing a gradient strain to an extracellular matrix to induce mechanotransduction. The gradient strain can be produced by adhering the extracellular matrix to a post and the walls of a sample holder, and then rotating the post and the sample holder. This strain can result in increased stiffness of the extracellular matrix with very little loss of pore size.