The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2014

Filed:

Jul. 01, 2009
Applicants:

Robert A. Heald, Harlow Essex, GB;

Philip Jackson, Harlow Essex, GB;

Joseph P. Lyssikatos, Piedmont, CA (US);

Stephen Price, Harlow Essex, GB;

Pascal Pierre Alexandre Savy, Harlow Essex, GB;

Inventors:

Robert A. Heald, Harlow Essex, GB;

Philip Jackson, Harlow Essex, GB;

Joseph P. Lyssikatos, Piedmont, CA (US);

Stephen Price, Harlow Essex, GB;

Pascal Pierre Alexandre Savy, Harlow Essex, GB;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 275/04 (2006.01); C07D 231/56 (2006.01); C07D 513/04 (2006.01); C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61K 31/428 (2006.01); A61K 31/416 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to bicyclic heterocycles of formulae I and II with anti-cancer and/or anti-inflammatory activity and more specifically with MEK kinase inhibitory activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth, treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.


Find Patent Forward Citations

Loading…