The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2014
Filed:
Apr. 24, 2008
Applicants:
Per Bjork, Lund, SE;
Frederik Ivars, Lund, SE;
Tomas Leanderson, Lund, SE;
Inventors:
Assignee:
Active Biotech, AB, Lund, SE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 14/52 (2006.01); G01N 33/566 (2006.01); G01N 33/68 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 14/52 (2013.01); C07K 16/18 (2013.01); C07K 2316/96 (2013.01); G01N 33/566 (2013.01); G01N 33/6842 (2013.01); G01N 2500/00 (2013.01); G01N 2333/70503 (2013.01); G01N 2333/705 (2013.01); C07K 14/705 (2013.01); C07K 2317/56 (2013.01);
Abstract
A method of identifying a compound for use in therapy which modulates the interaction of S1OO A9 with a ligand comprising:—determining whether a candidate compound is capable of modulating the interaction of S1OO A9 with RAGE or the interaction of S1OO A9 with a TLR (Toll like receptor), or—determining whether a candidate compound is capable of binding to S100A9 in a manner which disrupts binding of S1OO A9 with RAGE or the binding of S100A9 with a TLR, to thereby identify whether the compound may be used in therapy.