The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2014

Filed:

Sep. 22, 2011
Applicants:

LI Chen, Shanghai, CN;

Michael Patrick Dillon, San Fracisco, CA (US);

Lichun Feng, Shanghai, CN;

Ronald Charles Hawley, Mountain View, CA (US);

Minmin Yang, Nanjing, CN;

Inventors:

Li Chen, Shanghai, CN;

Michael Patrick Dillon, San Fracisco, CA (US);

Lichun Feng, Shanghai, CN;

Ronald Charles Hawley, Mountain View, CA (US);

Minmin Yang, Nanjing, CN;

Assignee:

Roche Palo Alto LLC, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); C07D 213/12 (2006.01); C07D 471/04 (2006.01); C07D 401/10 (2006.01); C07D 405/12 (2006.01); C07D 257/04 (2006.01); C07D 409/14 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 471/04 (2013.01); C07D 401/10 (2013.01); C07D 405/12 (2013.01); C07D 257/04 (2013.01); C07D 409/14 (2013.01);
Abstract

Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, Ris optionally substituted tetrazolyl, Ris optionally substituted phenyl, optionally substituted pyridinyl or optionally substituted thienyl, and R, R, R, RRand Rare as defined herein. Also provided are methods of using the compounds for treating diseases associated with the P2Xand/or a P2Xreceptor antagonist and methods of making the compounds.


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