The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2014

Filed:

Oct. 11, 2010
Applicants:

Paul David Ratcliffe, Newhouse, GB;

Thomas Russell Clarkson, Newhouse, GB;

Fiona Jeremiah, Newhouse, GB;

John Kinnard Ferguson Maclean, Brookline, MA (US);

Inventors:

Paul David Ratcliffe, Newhouse, GB;

Thomas Russell Clarkson, Newhouse, GB;

Fiona Jeremiah, Newhouse, GB;

John Kinnard Ferguson MacLean, Brookline, MA (US);

Assignee:

Merck Sharp & Dohme B.V., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/08 (2006.01); C07D 519/00 (2006.01); C07D 471/08 (2006.01); A61K 31/551 (2006.01); A61K 31/517 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a heterocyclic derivative of formula (I) wherein the variables are as defined in the specification or to a pharmaceutically acceptable salt or solvate thereof. The present invention further relates to pharmaceutical compositions comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of disorders mediated by nicotinic acetylcholine receptors, such as schizophrenia and Alzheimer's disease.


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