The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2014
Filed:
May. 19, 2010
Diana Hall, Lausanne, CH;
Maria Jimenez, Chavannes-Pres-Renens, CH;
Carine Poussin, Evian-les-Bains, FR;
Bernard Thorens, Epalinges, CH;
Diana Hall, Lausanne, CH;
Maria Jimenez, Chavannes-Pres-Renens, CH;
Carine Poussin, Evian-les-Bains, FR;
Bernard Thorens, Epalinges, CH;
Sanofi, Paris, FR;
Abstract
The present invention concerns Zdhhc2, a new target involved in adipogenesis modulation. Using a siRNA approach, the inventors demonstrated that decrease in Zdhhc2 activity in adipose tissue induces a decrease in adipogenesis. Thus, the present invention relates to modulators of Zdhhc2 activity as well as screening test for identification of modulators of the activity of this target, and their use, especially in pharmaceutical composition, to modulate adipogenesis and thus treat obesity and related disorders.