The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2014
Filed:
May. 07, 2009
Hiromu Suzuki, Hokkaido, JP;
Minoru Toyota, Hokkaido, JP;
Kohzoh Imai, Hokkaido, JP;
Yasuhisa Shinomura, Hokkaido, JP;
Takashi Tokino, Hokkaido, JP;
Hiromu Suzuki, Hokkaido, JP;
Minoru Toyota, Hokkaido, JP;
Kohzoh Imai, Hokkaido, JP;
Yasuhisa Shinomura, Hokkaido, JP;
Takashi Tokino, Hokkaido, JP;
Sapporo Medical University, Hokkaido, JP;
Abstract
The object aims to comprehensively analyze miRNA that undergoes epigenetic silencing in cancer to identify miRNA associated with cancer, elucidate the role of the identified miRNA in cancer, and develop a novel method for detecting cancer and a novel therapeutic agent for cancer both of which relate to the miRNA. Disclosed is a method for detecting cancer in a subject, which comprises detecting methylated CpG in a CpG island located in a promoter region of a microRNA 34b gene and/or a microRNA 34c gene in a biological sample collected from the subject. Also disclosed is a therapeutic agent for cancer, which comprises a nucleic acid encoding a BTG4 gene or BTG4, or comprises a nucleic acid encoding a miR-34b gene and/or an miR-34c gene or miR-34b and/or miR-34c.