The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2014

Filed:

Jun. 18, 2013
Applicant:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Inventors:

Leslie B. Poole, Tobaccoville, NC (US);

S. Bruce King, Walnut Cove, NC (US);

Jacquelyn S. Fetrow, Winston-Salem, NC (US);

Assignee:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/52 (2006.01); G01N 21/64 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/68 (2013.01); G01N 33/6815 (2013.01); G01N 21/6428 (2013.01); G01N 33/574 (2013.01);
Abstract

The present invention provides compounds of Formula I: wherein: Ris a label (e.g., a detectable group and an anti-tumor agent); L is present or absent and when present is a linking group; and x represents an integer from 1 to 10; or a pharmaceutically acceptable salt thereof. The compounds are useful for, among other things, identifying cysteine sulfenic acids in proteins and monitoring oxidative damage in proteins and cells. Adduct formation can be detected using analytical methods such as electrospray ionization mass spectrometry and fluorescence.


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Poole, Leslie. (2014). Method for detecting compounds containing sulfenic acid using a 1,3-cyclohexanedione-based probe (U.S. Patent No. 8841132). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8841132

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