The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2014
Filed:
Dec. 14, 2007
Peter Schwind, Fribourg, CH;
Iwan Aebischer, Fribourg, CH;
Peter Schwind, Fribourg, CH;
Iwan Aebischer, Fribourg, CH;
Medion Diagnostics AG, Dudingen, CH;
Abstract
The invention relates to a method for determining one or more cellularly bound analytes in a liquid sample, said method being carried out using a device comprising: at least one feeding zone () for applying the liquid sample; a porous membrane () that is suitable for letting cellular components penetrate therethrough and includes at least one indicator zone on the membrane, said indicator zone being able to interact with the cellularly bound analyte and containing at least one binding element against the cellularly bound analyte; and at least one absorption area () on the membrane, which absorbs the liquid after the liquid has passed the indicator zones. The at least one indicator zone lies between the feeding zone () and the absorption area (). The method is carried out for concentrating and quantifying the minor cell population in heterogeneous cell populations, for example in cases of fetomaternal hemorrhage or in chimera, detecting an analyte provided at a low concentration on cells, determining the hematocrit value, and/or determining, in parallel, cellularly bound analytes in mixed-field reactions.