The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2014
Filed:
May. 25, 2012
Applicants:
Yuhua LI, Newark, DE (US);
Benjamin Chien, Newark, DE (US);
Inventors:
Yuhua Li, Newark, DE (US);
Benjamin Chien, Newark, DE (US);
Assignee:
Foresec Pharmaceuticals, LLC, Newark, DE (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/25 (2006.01); A61K 38/47 (2006.01); A61K 47/48 (2006.01); A61K 9/19 (2006.01); A61K 9/00 (2006.01); A61K 38/26 (2006.01); A61K 38/29 (2006.01); A61K 38/18 (2006.01); A61K 38/22 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1808 (2013.01); A61K 47/48215 (2013.01); A61K 47/48046 (2013.01); A61K 9/19 (2013.01); A61K 9/0024 (2013.01); A61K 9/0019 (2013.01); A61K 47/48038 (2013.01); A61K 38/25 (2013.01); A61K 38/26 (2013.01); A61K 38/47 (2013.01); A61K 38/29 (2013.01); A61K 38/2278 (2013.01);
Abstract
The present invention provides methods of forming a solid, biodegradable implant in-situ in a body by administering a liquid pharmaceutical composition comprising an effective amount of a biocompatible, water-insoluble, biodegradable polymer and an effective amount of a therapeutic peptide covalently modified with one or more lipophilic or amphiphilic moieties, which are dissolved or dispersed in a biocompatible, water-soluble organic solvent. This invention also provides related compositions and methods.