The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2014
Filed:
Oct. 27, 2010
Applicants:
Dirk Nagorsen, Munich, DE;
Peter Kufer, Munich, DE;
Gerhard Zugmaier, Munich, DE;
Patrick Baeuerle, Munich, DE;
Inventors:
Dirk Nagorsen, Munich, DE;
Peter Kufer, Munich, DE;
Gerhard Zugmaier, Munich, DE;
Patrick Baeuerle, Munich, DE;
Assignee:
Micromet AG, Munich, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); G01N 33/50 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 2039/55 (2013.01); C07K 2317/31 (2013.01); G01N 2800/52 (2013.01); A61K 2039/505 (2013.01); G01N 33/5052 (2013.01); C07K 16/2809 (2013.01); G01N 33/505 (2013.01); A61K 2039/545 (2013.01);
Abstract
Provided herein is a method for assessing the risk of potential adverse effects for a human patient mediated by the administration of a CD19.times.CD3 bispecific antibody to said patient comprising determining the ratio of B cells to T cells of said patient, wherein a ratio of about 1:5 or lower is indicative for a risk of potential adverse effects for said patient.