The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2014
Filed:
May. 20, 2011
Applicants:
Wei-ching Liang, Foster City, CA (US);
Gregory D. Plowman, San Carlos, CA (US);
Yan Wu, Foster City, CA (US);
Weilan YE, Foster City, CA (US);
Inventors:
Wei-Ching Liang, Foster City, CA (US);
Gregory D. Plowman, San Carlos, CA (US);
Yan Wu, Foster City, CA (US);
Weilan Ye, Foster City, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2842 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); A61K 2039/507 (2013.01); C07K 2317/24 (2013.01); C07K 2317/92 (2013.01); C07K 2316/96 (2013.01);
Abstract
The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-α5β1 antibodies and methods of making and using them.