The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2014

Filed:

Nov. 12, 2009
Applicants:

Noriko Suenobu, Yokohama, JP;

Chihiro Kondo, Yokohama, JP;

Takashi Yamasaki, Yokohama, JP;

Inventors:

Noriko Suenobu, Yokohama, JP;

Chihiro Kondo, Yokohama, JP;

Takashi Yamasaki, Yokohama, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 8/46 (2006.01); A61K 8/44 (2006.01); C07C 321/14 (2006.01); C07C 309/04 (2006.01); C07C 309/07 (2006.01); C07C 309/18 (2006.01); A61Q 19/08 (2006.01); A61K 8/42 (2006.01); A61K 31/198 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61Q 19/08 (2013.01); A61K 8/46 (2013.01); A61K 8/466 (2013.01); A61K 8/42 (2013.01);
Abstract

Provided are anti-wrinkle agents having a novel scaffold that is suitable as components for external skin preparations such as cosmetics. The anti-wrinkle agents comprise compounds represented by general formula (1), stereoisomers thereof, or pharmacologically acceptable salts thereof. Said anti-wrinkle agents have excellent efficacy in improving wrinkles and sagging that are caused by skin aging with increased age or occur as a result of photoaging due to ultraviolet rays exposure. [In the formula, Rrepresents a hydrogen atom or a 1 to 8 carbon straight or branched alkyl group. Rrepresents —SH, —SOH, —S—S—X, —S—X, —SO—X, —SO—X, —SO—NY—Xor —SO—NY—Y. X-Xindependently are hydrogen atoms or 1 to 8 carbon aliphatic hydrocarbon groups or 5 to 12 carbon aromatic moiety wherein carbon atoms may be substituted with heteroatoms. Yto Yindependently represent hydrogen atoms or 1 to 8 carbon linear or branched alkyl groups. Rrepresents a hydrogen atom or acyl group having a 1 to 8 carbon straight or branched alkyl chain. Rrepresents a 5 to 12 carbon aromatic group or polycyclic condensed aromatic group that may have unsubstituted or substituted groups. m represents an integer 0-3 and n represents an integer 1 or 2].


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