The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2014

Filed:

May. 05, 2010
Applicants:

François Paul Bischoff, Vosselaar, BE;

Henricus Jacobus Maria Gijsen, Breda, NL;

Serge Maria Aloysius Pieters, Hulst, NL;

Garrett Berlond Minne, Kalken, BE;

Assignees:

Janssen Pharmaceuticals, Inc., Titusville, NJ (US);

Cellzome Limited, Brentford, Middlesex, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4178 (2006.01); A61K 31/437 (2006.01); C07D 471/04 (2006.01); C07D 413/14 (2006.01); A61P 25/28 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 403/14 (2013.01);
Abstract

The present invention is concerned with novel substituted indazole and aza-indazole derivatives of Formula (I) wherein R, R, R, R, Y, A, A, A, A, X, X, Xand Hethave the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.


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