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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8835440 B1

PDFFull Text
Date of Patent:
Sep. 16, 2014

Filed:

Jul. 24, 2013

Cyclic pyrimidin-4-carboxamides as ccr2 receptor antagonists for treatment of inflammation, asthma and copd

Applicants:

Heiner Ebel, Biberach an der Riss, DE;

Sara Frattini, Castelleone, IT;

Riccardo Giovannini, Verona, IT;

Christoph Hoenke, Biberach an der Riss, DE;

Thomas Trieselmann, Mettenberg, DE;

Patrick Tielmann, Bad Soden am Taunus, DE;

Stefan Scheuerer, Warthausen, DE;

Silke Hobbie, Biberach an der Riss, DE;

Frank Buettner, Attenweiler, DE;

Inventors:

Heiner Ebel, Biberach an der Riss, DE;

Sara Frattini, Castelleone, IT;

Riccardo Giovannini, Verona, IT;

Christoph Hoenke, Biberach an der Riss, DE;

Thomas Trieselmann, Mettenberg, DE;

Patrick Tielmann, Bad Soden am Taunus, DE;

Stefan Scheuerer, Warthausen, DE;

Silke Hobbie, Biberach an der Riss, DE;

Frank Buettner, Attenweiler, DE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:

Michael P. Morris

Edward S. Lazer

Primary Examiner:

James O Wilson

Assistant Examiner:

Alexander R Pagano

Int. Cl.
CPC ...
A01N 43/54 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01); C07D 498/10 (2006.01); C07D 403/06 (2006.01); A61K 31/55 (2006.01); C07D 491/052 (2006.01); C07D 401/06 (2006.01); A61K 31/553 (2006.01); C07D 405/14 (2006.01); C07D 471/10 (2006.01); C07D 407/14 (2006.01); C07D 417/14 (2006.01); A61K 31/5377 (2006.01); A61K 31/551 (2006.01); C07D 471/04 (2006.01); C07D 403/14 (2006.01); C07D 451/02 (2006.01); C07D 401/14 (2006.01); A61K 31/506 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); C07D 498/10 (2013.01); C07D 403/06 (2013.01); A61K 31/55 (2013.01); C07D 491/052 (2013.01); C07D 401/06 (2013.01); A61K 31/553 (2013.01); C07D 405/14 (2013.01); C07D 471/10 (2013.01); C07D 407/14 (2013.01); C07D 417/14 (2013.01); A61K 31/5377 (2013.01); A61K 31/551 (2013.01); C07D 471/04 (2013.01); C07D 403/14 (2013.01); C07D 451/02 (2013.01); C07D 401/14 (2013.01); C07D 413/14 (2013.01);
Abstract

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.

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