The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2014

Filed:

Jul. 08, 2013
Applicant:

Takeda Pharmaceutical Company Limited, San Diego, CA (US);

Inventors:

Edcon Chang, San Diego, CA (US);

Wolfgang Reinhard Ludwig Notz, San Diego, CA (US);

Michael B. Wallace, San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/395 (2006.01); A61K 31/535 (2006.01); A61K 31/519 (2006.01); A61K 31/52 (2006.01); A61K 31/522 (2006.01); A61K 31/505 (2006.01); C07D 413/14 (2006.01); C07D 487/04 (2006.01); C07D 473/02 (2006.01); C07D 403/12 (2006.01); C07D 519/00 (2006.01); A61K 31/5377 (2006.01); C07D 491/107 (2006.01); A61K 45/06 (2006.01); A61K 31/506 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 519/00 (2013.01); A61K 31/5377 (2013.01); A61K 31/52 (2013.01); C07D 491/107 (2013.01); A61K 45/06 (2013.01); C07D 487/04 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01);
Abstract

Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R, R, R, R, R, R, R, R, R, and Rare defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating immunological disorders, cardiovascular disease, cancer, and other diseases, disorders or conditions associated with PI3Kδ.


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