The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2014

Filed:

Mar. 10, 2011
Applicants:

Xiuzhi Susan Sun, Manhattan, KS (US);

Hongzhou Huang, Manhattan, KS (US);

Inventors:

Xiuzhi Susan Sun, Manhattan, KS (US);

Hongzhou Huang, Manhattan, KS (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); C07K 7/08 (2006.01); C07K 14/00 (2006.01); A61L 27/22 (2006.01); A61K 51/12 (2006.01); A61L 27/52 (2006.01); C07K 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/00 (2013.01); A61L 27/22 (2013.01); A61K 51/1213 (2013.01); A61K 38/10 (2013.01); A61L 27/52 (2013.01); C07K 7/00 (2013.01);
Abstract

The present invention broadly provides novel peptides that can be used to form hydrogels. The peptides are short (preferably 30 amino acid residues or less) and include hydrophilic and hydrophobic segments joined by a turning segment. The hydrogels are formed by altering the pH of a solution of these peptides to an acidic level, or by introducing a source of ions into a solution of these peptides. The resulting hydrogels are shear thinning gels that have high storage moduli and high rates of recovery after destruction. They find use in medical applications, including tissue engineering.


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