The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2014
Filed:
Sep. 08, 2008
Yingmei Han, Tianjin, CN;
Guangping Xia, Tianjin, CN;
Weiren Xu, Tianjin, CN;
Zhuanyou Zhao, Tianjin, CN;
Wulin Liu, Tianjin, CN;
Naxia Zhao, Tianjin, CN;
Peng Liu, Tianjin, CN;
Shijun Zhang, Tianjin, CN;
Xiaoli Fu, Tianjin, CN;
Yuli Wang, Tianjin, CN;
Weiting Wang, Tianjin, CN;
Lida Tang, Tianjin, CN;
Yingmei Han, Tianjin, CN;
Guangping Xia, Tianjin, CN;
Weiren Xu, Tianjin, CN;
Zhuanyou Zhao, Tianjin, CN;
Wulin Liu, Tianjin, CN;
Naxia Zhao, Tianjin, CN;
Peng Liu, Tianjin, CN;
Shijun Zhang, Tianjin, CN;
Xiaoli Fu, Tianjin, CN;
Yuli Wang, Tianjin, CN;
Weiting Wang, Tianjin, CN;
Lida Tang, Tianjin, CN;
Tianjin Institute of Pharmaceutical Research, Tianjin, CN;
Abstract
This invention provides a method for preparing cycloastragenol monoglucoside CMG (cycloastragenol-6-O-β-D-glucoside), comprising the steps of: a. using astragaloside IV or Astragali extracts prepared by a conventional method as raw materials and adding an appropriate solvent thereinto to form a raw material solution; b. adding hydrolase and allowing for hydrolysis at a constant temperature to obtain a hydrolysate; c. separating the hydrolysate with macroporous adsorption resin; and d. obtaining the product by purification and separation. The present invention further provides cycloastragenol-6-O-β-D-glucoside prepared according to the method of this invention as well as its use in the preparation of a medicament for treating cardiovascular diseases and pharmaceutical compositions comprising the same.